Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2539PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: tgr:Tgr7_3068 suppressor for copper-sensitivity D, putative. (173 aa)    
Predicted Functional Partners:
Slit_2540
KEGG: net:Neut_2524 RNA-binding S4 domain-containing protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein.
       0.693
Slit_2541
Lysine decarboxylase; KEGG: mms:mma_1191 arginine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein.
       0.688
dcd
Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
  
    0.553
Slit_2538
KEGG: mag:amb0272 hypothetical protein.
       0.499
Slit_2542
KEGG: lhk:LHK_01827 hypothetical protein.
       0.496
Slit_0866
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: lch:Lcho_1553 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
  
 0.490
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
   0.431
Slit_2545
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: tcu:Tcur_2047 pyridine nucleotide-disulphide oxidoreductase dimerization region.
 
   
 0.424
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
    0.417
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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