Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2542KEGG: lhk:LHK_01827 hypothetical protein. (73 aa)    
Predicted Functional Partners:
dcd
Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
 
     0.804
Slit_1251
PFAM: nitroreductase; KEGG: bur:Bcep18194_B1060 hypothetical protein.
 
  
 0.596
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
    0.555
Slit_2541
Lysine decarboxylase; KEGG: mms:mma_1191 arginine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein.
       0.551
Slit_2540
KEGG: net:Neut_2524 RNA-binding S4 domain-containing protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein.
       0.547
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
       0.545
Slit_2545
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: tcu:Tcur_2047 pyridine nucleotide-disulphide oxidoreductase dimerization region.
  
  
 0.511
Slit_2539
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: tgr:Tgr7_3068 suppressor for copper-sensitivity D, putative.
       0.496
Slit_1291
ZipA FtsZ-binding region; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.486
Slit_1435
KEGG: mfa:Mfla_1470 amine oxidase; TIGRFAM: squalene-associated FAD-dependent desaturase; PFAM: amine oxidase.
  
     0.464
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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