Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Slit_2549KEGG: azo:azo1111 putative hemerythrin-like protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein. (129 aa)    
Predicted Functional Partners:
Slit_2092
KEGG: tmz:Tmz1t_0858 hemerythrin-like metal-binding protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein.
  
     0.775
Slit_2372
KEGG: aeh:Mlg_0407 hypothetical protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein.
  
     0.775
Slit_2822
KEGG: aeh:Mlg_0407 hypothetical protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein.
  
     0.775
atpD
V-type ATPase, D subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.625
atpB
H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
       0.625
atpA
H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.
       0.625
Slit_2553
PFAM: H+transporting two-sector ATPase E subunit; KEGG: noc:Noc_2084 H+-transporting two-sector ATPase, E subunit.
       0.625
Slit_2554
KEGG: noc:Noc_2085 hypothetical protein.
       0.625
Slit_2555
PFAM: H+transporting two-sector ATPase C subunit; KEGG: noc:Noc_2086 H+-transporting two-sector ATPase, C subunit.
       0.625
Slit_2556
PFAM: V-type ATPase 116 kDa subunit; KEGG: noc:Noc_2087 V-type ATPase, 116 kDa subunit; Belongs to the V-ATPase 116 kDa subunit family.
       0.558
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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