Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
atpAH(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (599 aa)    
Predicted Functional Partners:
atpD
V-type ATPase, D subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpB
H(+)-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.
 
0.999
Slit_2553
PFAM: H+transporting two-sector ATPase E subunit; KEGG: noc:Noc_2084 H+-transporting two-sector ATPase, E subunit.
 
 0.999
Slit_2557
PFAM: H+transporting two-sector ATPase C (AC39) subunit; KEGG: noc:Noc_2088 H+-transporting two-sector ATPase, C (AC39) subunit.
 
 0.999
Slit_2555
PFAM: H+transporting two-sector ATPase C subunit; KEGG: noc:Noc_2086 H+-transporting two-sector ATPase, C subunit.
 
 0.998
Slit_2556
PFAM: V-type ATPase 116 kDa subunit; KEGG: noc:Noc_2087 V-type ATPase, 116 kDa subunit; Belongs to the V-ATPase 116 kDa subunit family.
 
 0.998
Slit_2554
KEGG: noc:Noc_2085 hypothetical protein.
  
 0.997
atpE
ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 0.976
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
   
 
 0.927
Slit_2558
KEGG: noc:Noc_2089 H+-ATPase, subunit H.
       0.692
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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