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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lolAOuter membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (204 aa)    
Predicted Functional Partners:
Slit_1402
KEGG: mmb:Mmol_0641 lipoprotein releasing system, transmembrane protein, LolC/E family; TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214.
 
 
 
 0.869
Slit_2574
PFAM: protein of unknown function DUF214; KEGG: mxa:MXAN_6403 putative ABC transporter, permease protein.
   
 
 0.841
Slit_2578
KEGG: app:CAP2UW1_3128 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase.
  
    0.829
Slit_2580
KEGG: nmu:Nmul_A0176 cell division FtsK/SpoIIIE; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: DNA translocase ftsK gamma; AAA ATPase.
 
  
 0.805
lolD
Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
   
 
 0.800
Slit_1135
KEGG: dar:Daro_1671 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
   
 
 0.789
bamA
Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
   
 0.759
lptD
Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
  
   
 0.736
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
      0.734
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
    0.684
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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