Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2607PFAM: Type II secretion system F domain; KEGG: har:HEAR1952 type IV pilus assembly protein TapC. (413 aa)    
Predicted Functional Partners:
Slit_2608
KEGG: har:HEAR1953 general secretion pathway protein E (type II traffic warden ATPase); PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase.
 
   0.969
Slit_0536
KEGG: net:Neut_2128 putative GAF sensor protein; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; GAF domain protein; SMART: GAF domain protein; AAA ATPase.
 
 
 0.875
Slit_0498
General secretory pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
   0.872
Slit_0685
KEGG: app:CAP2UW1_0626 type II secretion system protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase.
 
   0.872
Slit_2073
KEGG: dar:Daro_1151 type II secretion system protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase.
 
   0.872
Slit_1830
PFAM: type II secretion system protein E; KEGG: tbd:Tbd_1295 type II secretion system protein.
 
   0.870
Slit_2606
KEGG: har:HEAR1951 hypothetical protein.
  
    0.846
Slit_2700
Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.828
Slit_2759
TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: dar:Daro_3883 pilus retraction protein PilT; SMART: AAA ATPase.
 
  
 0.776
Slit_2593
PFAM: type II and III secretion system protein; Secretin/TonB short domain; KEGG: har:HEAR1939 mannose-sensitive hemagglutinin L.
 
  
 0.774
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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