Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_2615PFAM: O-antigen polymerase; KEGG: bte:BTH_I0650 O-antigen polymerase family protein. (597 aa)    
Predicted Functional Partners:
gpsA
KEGG: tbd:Tbd_2404 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
       0.776
Slit_2611
PFAM: protein of unknown function DUF1058; KEGG: eba:ebA1059 of unknown function.
       0.773
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
       0.773
Slit_2613
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
       0.773
Slit_2614
KEGG: tbd:Tbd_2399 rhodanese-like protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
       0.773
Slit_2616
KEGG: dar:Daro_3342 hypothetical protein.
       0.773
Slit_2617
PFAM: acriflavin resistance protein; KEGG: tbd:Tbd_2397 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
       0.689
Slit_2618
KEGG: tbd:Tbd_2396 secretion protein HlyD; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.689
Slit_2903
TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: tgr:Tgr7_2079 mannose-1-phosphate guanylyltransferase (GDP); PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase.
  
  
 0.616
Slit_2619
KEGG: tbd:Tbd_2395 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR.
       0.495
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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