STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2634KEGG: app:CAP2UW1_0767 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein. (541 aa)    
Predicted Functional Partners:
Slit_2633
KEGG: app:CAP2UW1_0768 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase.
 
 0.995
Slit_0436
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 0.918
Slit_2632
N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; KEGG: neu:NE2182 N-acetyl-anhydromuranmyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2.
       0.806
Slit_2635
KEGG: nmu:Nmul_A1813 hypothetical protein.
       0.806
Slit_2940
KEGG: tbd:Tbd_2552 response regulator receiver domain-containing protein; PFAM: response regulator receiver; SMART: response regulator receiver.
  
 
 
 0.783
Slit_2939
KEGG: app:CAP2UW1_3587 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
  
 
 
 0.774
Slit_0007
KEGG: mfa:Mfla_0188 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
  
     0.754
Slit_2936
KEGG: app:CAP2UW1_3590 CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; SMART: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein.
  
   
 0.749
Slit_0111
PFAM: Pilus assembly protein PilP; KEGG: tbd:Tbd_0205 type IV pilus assembly protein PilP.
  
     0.738
Slit_0108
TIGRFAM: type IV pilus assembly protein PilM; KEGG: dar:Daro_0210 type IV pilus assembly protein PilM.
  
     0.727
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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