Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2677Peroxiredoxin; KEGG: mfa:Mfla_1689 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Peroxiredoxin-like. (200 aa)    
Predicted Functional Partners:
Slit_0866
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: lch:Lcho_1553 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
  
 
 0.928
fur
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: mei:Msip34_1882 ferric uptake regulator, Fur family; Belongs to the Fur family.
  
  
 0.780
Slit_2675
KEGG: tbd:Tbd_1001 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.776
Slit_2768
PFAM: cytochrome c biogenesis protein transmembrane region; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: oca:OCAR_6268 cytochrome c biogenesis protein, transmembrane region.
  
 0.736
Slit_0525
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: lch:Lcho_1553 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
  
 
 0.722
Slit_0713
Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
  
 
 0.722
Slit_1881
TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: RQC domain; DEAD/DEAH box helicase domain protein; helicase domain protein; HRDC domain protein; KEGG: mfa:Mfla_1097 ATP-dependent DNA helicase RecQ; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein.
    
   0.697
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.680
hscA
Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
   
 
 0.680
Slit_1017
KEGG: aeh:Mlg_2566 DJ-1 family protein; TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein.
  
 
 0.643
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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