node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Slit_0690 | Slit_1601 | Slit_0690 | Slit_1601 | KEGG: tbd:Tbd_1900 ABC transporter ATPase; PFAM: ABC transporter related; SMART: AAA ATPase. | KEGG: rfr:Rfer_2722 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. | 0.909 |
Slit_0690 | msbA | Slit_0690 | Slit_2679 | KEGG: tbd:Tbd_1900 ABC transporter ATPase; PFAM: ABC transporter related; SMART: AAA ATPase. | Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.908 |
Slit_0982 | lpxK | Slit_0982 | Slit_1364 | KEGG: nmu:Nmul_A0682 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.429 |
Slit_0982 | msbA | Slit_0982 | Slit_2679 | KEGG: nmu:Nmul_A0682 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. | Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.896 |
Slit_1601 | Slit_0690 | Slit_1601 | Slit_0690 | KEGG: rfr:Rfer_2722 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. | KEGG: tbd:Tbd_1900 ABC transporter ATPase; PFAM: ABC transporter related; SMART: AAA ATPase. | 0.909 |
Slit_1601 | dnaK | Slit_1601 | Slit_2130 | KEGG: rfr:Rfer_2722 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.589 |
Slit_1601 | lpxK | Slit_1601 | Slit_1364 | KEGG: rfr:Rfer_2722 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.820 |
Slit_1601 | msbA | Slit_1601 | Slit_2679 | KEGG: rfr:Rfer_2722 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. | Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.827 |
Slit_1605 | msbA | Slit_1605 | Slit_2679 | KEGG: rfr:Rfer_2722 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. | Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.837 |
Slit_2680 | msbA | Slit_2680 | Slit_2679 | KEGG: mmb:Mmol_0279 hypothetical protein. | Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.655 |
dnaK | Slit_1601 | Slit_2130 | Slit_1601 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | KEGG: rfr:Rfer_2722 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase. | 0.589 |
dnaK | msbA | Slit_2130 | Slit_2679 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.627 |
lpxA | lpxB | Slit_1639 | Slit_1638 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.993 |
lpxA | lpxC | Slit_1639 | Slit_2712 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.984 |
lpxA | lpxK | Slit_1639 | Slit_1364 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.855 |
lpxA | msbA | Slit_1639 | Slit_2679 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.590 |
lpxB | lpxA | Slit_1638 | Slit_1639 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.993 |
lpxB | lpxC | Slit_1638 | Slit_2712 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.866 |
lpxB | lpxK | Slit_1638 | Slit_1364 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.994 |
lpxB | msbA | Slit_1638 | Slit_2679 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. | 0.648 |