Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2681PFAM: TonB-dependent receptor plug; TonB-dependent receptor; KEGG: nmu:Nmul_A0628 TonB-dependent receptor. (670 aa)    
Predicted Functional Partners:
Slit_1365
PFAM: Biopolymer transport protein ExbD/TolR; KEGG: nmu:Nmul_A1028 biopolymer transport protein ExbD/TolR.
 
  
 0.582
Slit_1388
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.575
Slit_2680
KEGG: mmb:Mmol_0279 hypothetical protein.
       0.505
Slit_0507
TIGRFAM: TonB family protein; KEGG: neu:NE1626 putative TonB protein.
  
 
 0.484
Slit_0519
TIGRFAM: protein TolA; KEGG: neu:NE0217 hypothetical protein.
  
 
 0.484
Slit_1366
PFAM: MotA/TolQ/ExbB proton channel; KEGG: har:HEAR2492 putative biopolymer transport ExbB-like protein.
 
  
 0.466
Slit_0437
KEGG: app:CAP2UW1_4310 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
  
     0.450
msbA
Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
  
  
 0.444
Slit_1389
PFAM: MotA/TolQ/ExbB proton channel; KEGG: pag:PLES_01991 transport protein ExbB.
 
  
 0.415
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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