Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Slit_2700Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (286 aa)    
Predicted Functional Partners:
Slit_2699
PFAM: Type II secretion system F domain; KEGG: mei:Msip34_0586 type II secretion system protein.
 
  
 0.932
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.879
Slit_2759
TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: dar:Daro_3883 pilus retraction protein PilT; SMART: AAA ATPase.
 
   
 0.836
Slit_2607
PFAM: Type II secretion system F domain; KEGG: har:HEAR1952 type IV pilus assembly protein TapC.
 
  
 0.828
Slit_0497
KEGG: cvi:CV_3812 general secretion pathway protein F; TIGRFAM: general secretion pathway protein F; PFAM: Type II secretion system F domain.
 
  
 0.814
Slit_0684
PFAM: Type II secretion system F domain; KEGG: dar:Daro_3408 type II secretion system protein.
 
  
 0.810
Slit_0006
KEGG: nmu:Nmul_A0395 DNA processing protein DprA, putative; TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein.
  
  
 0.796
Slit_1831
PFAM: Type II secretion system F domain; KEGG: tbd:Tbd_1294 type II secretion system protein F.
 
  
 0.793
Slit_1396
TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; KEGG: nmu:Nmul_A2506 DNA internalization-related competence protein ComEC/Rec2; SMART: beta-lactamase domain protein.
 
  
 0.776
Slit_0536
KEGG: net:Neut_2128 putative GAF sensor protein; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; GAF domain protein; SMART: GAF domain protein; AAA ATPase.
 
 
 0.774
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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