Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2707KEGG: hna:Hneap_1461 putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding. (165 aa)    
Predicted Functional Partners:
Slit_0465
Putative transcriptional regulator, Crp/Fnr family; KEGG: pmy:Pmen_1780 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
  
  0.918
Slit_1220
KEGG: hna:Hneap_1461 putative transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
  
 
0.916
Slit_1242
Putative transcriptional regulator, Crp/Fnr family; KEGG: amr:AM1_2994 cyclic nucleotide-binding protein, putative; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
  
  0.912
Slit_1290
KEGG: tgr:Tgr7_0081 two component transcriptional regulator, AraC family; PFAM: metal-dependent phosphohydrolase HD sub domain; response regulator receiver; SMART: response regulator receiver; metal-dependent phosphohydrolase HD region.
    
  0.902
Slit_1432
Putative transcriptional regulator, Crp/Fnr family; KEGG: dal:Dalk_2479 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
     
  0.900
argJ
Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
       0.757
Slit_2553
PFAM: H+transporting two-sector ATPase E subunit; KEGG: noc:Noc_2084 H+-transporting two-sector ATPase, E subunit.
  
     0.707
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
       0.693
Slit_0420
KEGG: dar:Daro_2990 hypothetical protein.
  
     0.654
Slit_2704
Thiamine monophosphate synthase; KEGG: mfa:Mfla_2230 hypothetical protein; manually curated; PFAM: thiamine monophosphate synthase; NUDIX hydrolase.
       0.641
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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