STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2756PFAM: protein of unknown function YGGT; KEGG: nmu:Nmul_A0580 hypothetical protein. (188 aa)    
Predicted Functional Partners:
Slit_2755
PFAM: protein of unknown function DUF167; KEGG: nmu:Nmul_A0579 hypothetical protein; Belongs to the UPF0235 family.
  
  
 0.827
Slit_2758
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.739
Slit_1510
PFAM: Methyltransferase type 11; KEGG: tbd:Tbd_1664 methyl-transferase.
  
     0.731
zapD
Protein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
  
     0.720
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
    0.689
Slit_2095
KEGG: app:CAP2UW1_4067 hypothetical protein.
  
     0.648
Slit_2754
Cyclase/dehydrase; KEGG: pnu:Pnuc_2052 cyclase/dehydrase.
       0.608
Slit_0269
PFAM: protein of unknown function DUF513 hemX; KEGG: nmu:Nmul_A2688 hypothetical protein.
  
     0.597
Slit_1416
PFAM: Protein of unknown function DUF2133; KEGG: neu:NE0151 hypothetical protein.
  
     0.578
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.578
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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