Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2765PFAM: Protein of unknown function DUF2282, transmembrane; KEGG: cps:CPS_0845 hypothetical protein. (88 aa)    
Predicted Functional Partners:
Slit_2764
PFAM: protein of unknown function DUF692; KEGG: cvi:CV_3513 hypothetical protein.
 
  
 0.993
Slit_2763
PFAM: Protein of unknown function DUF2063; KEGG: cvi:CV_3514 hypothetical protein.
 
  
 0.978
Slit_2762
PFAM: DoxX family protein; KEGG: mpt:Mpe_A2957 hypothetical protein.
 
  
 0.971
Slit_0050
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase.
   
    0.639
Slit_0532
FHA domain containing protein; KEGG: dar:Daro_3359 forkhead-associated; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein.
   
    0.639
msrA-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
    0.592
Slit_1589
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: mei:Msip34_2713 anti-sigma-factor antagonist.
   
    0.513
msrB-2
TIGRFAM: methionine-R-sulfoxide reductase; KEGG: tel:tlr1214 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; Belongs to the MsrB Met sulfoxide reductase family.
  
    0.496
Slit_2766
KEGG: Os06g0112400; hypothetical protein.
       0.475
Slit_2304
PFAM: Hemolysin-type calcium-binding region; KEGG: rfr:Rfer_2715 VCBS.
   
    0.462
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.