Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2771RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: eli:ELI_10350 hypothetical protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2. (207 aa)    
Predicted Functional Partners:
Slit_2772
PFAM: protein of unknown function DUF1109; KEGG: rpt:Rpal_1069 protein of unknown function DUF1109.
     
 0.780
Slit_1275
PFAM: Anti sigma-E protein RseA family protein; KEGG: nmu:Nmul_A1747 anti sigma-E protein RseA.
  
 
 0.754
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.603
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.600
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.568
Slit_2770
KEGG: mag:amb4390 hypothetical protein.
       0.554
Slit_1702
RNA polymerase, sigma-24 subunit, ECF subfamily; KEGG: tbd:Tbd_1836 sigma-24 (FecI); TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.547
Slit_2768
PFAM: cytochrome c biogenesis protein transmembrane region; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: oca:OCAR_6268 cytochrome c biogenesis protein, transmembrane region.
 
   
 0.506
msrA-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
   
 0.488
Slit_2773
KEGG: tbd:Tbd_2617 hypothetical protein.
  
    0.478
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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