Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2800Putative transcriptional regulator, Crp/Fnr family; KEGG: hypothetical protein; K04739 cAMP-dependent protein kinase regulator; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding. (281 aa)    
Predicted Functional Partners:
Slit_2198
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; Ankyrin; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Ankyrin.
  
 
  0.778
Slit_0465
Putative transcriptional regulator, Crp/Fnr family; KEGG: pmy:Pmen_1780 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding.
  
     0.757
Slit_2097
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: dar:Daro_3414 adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
  
 
  0.746
Slit_1543
KEGG: app:CAP2UW1_0633 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 
  0.741
Slit_2071
Adenylate/guanylate cyclase; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: dal:Dalk_1258 adenylate/guanylate cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
  0.723
Slit_1739
Adenylate/guanylate cyclase with Chase sensor; KEGG: hha:Hhal_1889 putative adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 0.696
Slit_0050
KEGG: app:CAP2UW1_3892 adenylate/guanylate cyclase; PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 0.691
Slit_2048
KEGG: sse:Ssed_3621 putative adenylate/guanylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 0.670
Slit_0535
Putative transcriptional regulator, Crp/Fnr family; KEGG: mmb:Mmol_0609 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; Rhodanese domain protein; SMART: cyclic nucleotide-binding; Rhodanese domain protein.
  
    0.665
Slit_0252
Adenylate/guanylate cyclase with Chase sensor; KEGG: sat:SYN_01481 adenylate cyclase; PFAM: CHASE2 domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 0.663
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
Server load: low (10%) [HD]