STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apaHBis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (273 aa)    
Predicted Functional Partners:
Slit_2941
Cation transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.
 
      0.698
secE
Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.
  
     0.593
Slit_2872
PFAM: membrane bound O-acyl transferase MBOAT family protein; KEGG: tmz:Tmz1t_3262 membrane bound O-acyl transferase MBOAT family protein; Belongs to the membrane-bound acyltransferase family.
       0.539
Slit_2873
KEGG: vap:Vapar_4225 hypothetical protein.
  
    0.539
Slit_0585
Multi-sensor hybrid histidine kinase; KEGG: pin:Ping_2140 fused multi-sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; histidine kinase A domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; histidine kinase A domain protein; Hpt domain protein.
 
  
 0.492
Slit_0128
PFAM: DSBA oxidoreductase; KEGG: nmu:Nmul_A2454 DsbA oxidoreductase.
  
     0.482
bamE
SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
     0.480
ftsB
Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
     0.451
Slit_0648
PFAM: Stringent starvation protein B; KEGG: tbd:Tbd_1829 ClpXP protease specificity-enhancing factor.
  
     0.443
yidC
Membrane protein insertase, YidC/Oxa1 family domain containing protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
     0.438
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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