STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2903TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: tgr:Tgr7_2079 mannose-1-phosphate guanylyltransferase (GDP); PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase. (527 aa)    
Predicted Functional Partners:
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
 
 
 0.992
Slit_2101
Phosphomannomutase; KEGG: tbd:Tbd_2138 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase.
 
 0.988
Slit_2899
KEGG: avn:Avin_27780 glucose-1-phosphate cytidylyltransferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase.
  
 
 0.968
Slit_1773
PFAM: ROK family protein; KEGG: sfu:Sfum_0489 ROK family protein.
    
 0.950
pgi
KEGG: tgr:Tgr7_0871 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family.
  
 
 0.949
Slit_2909
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.945
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.927
Slit_1377
TIGRFAM: nucleotide sugar dehydrogenase; KEGG: cpc:Cpar_1724 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase.
  
 
 0.924
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.924
fbp
PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: noc:Noc_0021 fructose-1,6-bisphosphatase.
   
 0.922
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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