STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (696 aa)    
Predicted Functional Partners:
Slit_2731
KEGG: nmu:Nmul_A0434 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase.
 
 0.968
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.932
Slit_2953
PFAM: protein of unknown function DUF344; KEGG: glo:Glov_3059 protein of unknown function DUF344.
 
   
 0.808
Slit_2949
Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
       0.703
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
      0.595
purM
TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: nmn:NMCC_1133 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
    
 0.443
argA
TIGRFAM: amino-acid N-acetyltransferase; KEGG: nmu:Nmul_A0380 N-acetylglutamate synthase; PFAM: aspartate/glutamate/uridylate kinase; GCN5-related N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily.
       0.429
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.419
Slit_1065
KEGG: lhk:LHK_00522 PstA; TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component.
     
 0.419
Slit_1066
Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
     
 0.419
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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