Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Slit_2956KEGG: aav:Aave_0106 carbonic anhydrase family 3. (179 aa)    
Predicted Functional Partners:
Slit_2957
KEGG: app:CAP2UW1_1005 addiction module toxin, RelE/StbE family; TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system.
       0.773
Slit_2958
Transcriptional regulator, CopG family; PFAM: CopG domain protein DNA-binding domain protein; KEGG: app:CAP2UW1_1004 hypothetical protein.
       0.773
Slit_0028
KEGG: dvm:DvMF_0391 carbonate dehydratase; PFAM: carbonic anhydrase.
    
 
 0.745
Slit_2955
PFAM: Protein of unknown function DUF2288; KEGG: cja:CJA_2968 hypothetical protein.
       0.741
Slit_2954
KEGG: hypothetical protein.
       0.658
Slit_0986
KEGG: tbd:Tbd_2623 ribulose 1,5-bisphosphate carboxylase small subunit; PFAM: ribulose bisphosphate carboxylase small chain.
    
 
 0.591
Slit_0022
KEGG: tbd:Tbd_2638 ribulose bisphosphate carboxylase; PFAM: ribulose bisphosphate carboxylase large chain; Ribulose bisphosphate carboxylase, large subunit-like; Belongs to the RuBisCO large chain family.
    
 
 0.527
cbbL
Ribulose-bisphosphate carboxylase; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily.
    
 
 0.527
Slit_2959
Conserved hypothetical protein; Manually curated; KEGG: ppw:PputW619_2830 hypothetical protein.
       0.480
Slit_1856
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; KEGG: nmu:Nmul_A0097 3-hydroxyacyl-CoA dehydrogenase, NAD-binding.
  
  
 0.460
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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