Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
gmhASugar isomerase (SIS); Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (196 aa)    
Predicted Functional Partners:
Slit_0470
KEGG: mfa:Mfla_0643 D,D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Haloacid dehalogenase domain protein hydrolase.
  
 0.996
Slit_2967
rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
   
 0.994
Slit_2055
rfaE bifunctional protein; KEGG: dar:Daro_1285 D-alpha,beta-D-heptose 7-phosphate 1-kinase; TIGRFAM: rfaE bifunctional protein; PFAM: PfkB domain protein.
  
 0.990
Slit_2966
PFAM: transport-associated; KEGG: eba:ebA1464 hypothetical protein.
  
    0.868
Slit_2968
PFAM: protein of unknown function DUF971; KEGG: azo:azo0163 hypothetical protein.
       0.773
Slit_0315
PFAM: glycosyl transferase family 9; KEGG: pol:Bpro_0465 glycosyl transferase family protein.
 
   
 0.768
Slit_2905
PFAM: glycosyl transferase family 9; KEGG: cbd:CBUD_2105 ADP-heptose--LPS heptosyltransferase.
 
   
 0.747
Slit_2964
PFAM: protein of unknown function UPF0102; KEGG: cti:RALTA_A3032 conserved hypothetical protein, UPF0102; Belongs to the UPF0102 family.
  
    0.718
Slit_2963
PFAM: LppC family lipoprotein; KEGG: mfa:Mfla_2282 putative lipoprotein-like protein.
  
    0.717
Slit_2100
Manually curated; TIGRFAM: lipopolysaccharide heptosyltransferase II; KEGG: cvi:CV_2092 ADP-heptose--LPS heptosyltransferase II; PFAM: glycosyl transferase family 9.
 
   
 0.646
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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