Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Slit_2990PFAM: Cobyrinic acid ac-diamide synthase; KEGG: nmu:Nmul_A2768 cobyrinic acid a,c-diamide synthase. (259 aa)    
Predicted Functional Partners:
Slit_2989
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: app:CAP2UW1_4360 ParB-like partition protein; SMART: ParB domain protein nuclease; Belongs to the ParB family.
 
 0.991
rsmG
Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
 
  
 0.948
mnmG
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
  
    0.813
atpB-2
ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
       0.732
Slit_2988
ATP synthase I chain; KEGG: tbd:Tbd_2804 hypothetical protein; manually curated; PFAM: ATP synthase I chain.
       0.705
yidC
Membrane protein insertase, YidC/Oxa1 family domain containing protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
     0.597
atpE
ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
       0.588
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
    0.548
Slit_2486
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; Pyruvate/ketoisovalerate oxidoreductase; KEGG: hha:Hhal_0066 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
  
 0.522
rpmH
Ribosomal protein L34; Manually curated; TIGRFAM: ribosomal protein L34; KEGG: dar:Daro_4204 50S ribosomal protein L34; PFAM: ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
     
 0.508
Your Current Organism:
Sideroxydans lithotrophicus
NCBI taxonomy Id: 580332
Other names: S. lithotrophicus ES-1, Sideroxydans lithotrophicus ES-1, Sideroxydans lithotrophicus str. ES-1, Sideroxydans lithotrophicus strain ES-1, iron-oxidizing lithotroph ES-1
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