STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (246 aa)    
Predicted Functional Partners:
Tlie_0148
PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase; COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: dae:Dtox_3094 adenosylcobinamide-phosphateguanylyltransferase; PFAM: cobalbumin biosynthesis protein; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR:Adenosylcobinamide-phosphateguanylyltransferas e.
 
 
 0.997
Tlie_0146
PFAM: Phosphoglycerate mutase family; TIGRFAM: alpha-ribazole phosphatase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR017578: IPR001345: IPR013078; KEGG: slp:Slip_1453 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase; TIGRFAM: alpha-ribazole phosphatase.
 
 
 0.986
cobT
Nicotinate-nucleotide/dimethylbenzimidazolephosp horibosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.962
Tlie_1075
cob(I)yrinic acid a,c-diamide adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase; COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: tai:Taci_0126 cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Cob(I)alamin adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase.
 
 
 0.947
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.946
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 0.935
Tlie_0542
PFAM: Phosphoglycerate mutase family; TIGRFAM: alpha-ribazole phosphatase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078: IPR001345; KEGG: aco:Amico_1510 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase.
  
 
 0.935
Tlie_1515
PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase; COGs: COG2096 conserved hypothetical protein; InterPro IPR002779: IPR017858; KEGG: aco:Amico_0438 ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; SPTR: ATP/cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase.
    
 0.916
Tlie_0817
PFAM: Phosphoglycerate mutase family; TIGRFAM: alpha-ribazole phosphatase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: tai:Taci_0911 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase.
  
 
 0.677
Tlie_0193
Miro domain protein; PFAM: Ethanolamine utilisation - propanediol utilisation; TIGRFAM: ethanolamine utilization protein, EutP; COGs: COG4917 Ethanolamine utilization protein; InterPro IPR013684: IPR012381; KEGG: tai:Taci_0086 ethanolamine utilization protein-like protein; PFAM: Miro domain protein; SPTR: Ethanolamine utilization protein, EutP; Belongs to the EutP/PduV family.
  
    0.637
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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