STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0169Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: aco:Amico_0343 beta-lactamase domain protein; SPTR: Metallo-beta-lactamase family protein. (320 aa)    
Predicted Functional Partners:
Tlie_1656
PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR001763: IPR013027: IPR004099: IPR000815; KEGG: tai:Taci_0103 pyridine nucleotide-disulphide oxidoreductase dimerization region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.640
Tlie_0213
PFAM: Peptidase M15; InterPro IPR013230; KEGG: aco:Amico_1739 peptidase M15A; PFAM: Peptidase M15A; SPTR: Peptidase M15A.
  
    0.624
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.614
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
 
 0.591
Tlie_0170
PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family; COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852; KEGG: apo:Arcpr_1316 TRAP transporter solute receptor, TAXI family; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family.
       0.584
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
   
 
 0.571
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
  
   0.536
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.517
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.446
Tlie_0750
PFAM: Low molecular weight phosphotyrosine protein phosphatase; COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: tte:TTE0146 ribose 5-phosphate isomerase RpiB; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Ribose 5-phosphate isomerase RpiB.
   
   0.444
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.