| node1 | node2 | node1 annotation | node2 annotation | score |
| Tlie_0181 | Tlie_0182 | Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767: IPR000700; KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein. | PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: rer:RER_49240 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Putative GntR family transcriptional regulator. | 0.464 |
| Tlie_0181 | Tlie_0183 | Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767: IPR000700; KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein. | CoA-binding domain protein; PFAM: CoA binding domain; Formyl transferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR002376: IPR003781; KEGG: mpd:MCP_2918 acetyl-CoA synthetase; PFAM: CoA-binding domain protein; formyl transferase domain protein; SPTR: Acetyl coenzyme A synthetase (ADP forming), alpha domain protein. | 0.492 |
| Tlie_0181 | Tlie_0184 | Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767: IPR000700; KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein. | Pyruvate carboxyltransferase; PFAM: HMGL-like; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034: IPR000891; KEGG: aco:Amico_1308 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.453 |
| Tlie_0181 | Tlie_0185 | Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767: IPR000700; KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein. | PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839; KEGG: cth:Cthe_0363 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate/tyrosine/aromatic aminotransferase. | 0.422 |
| Tlie_0182 | Tlie_0181 | PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: rer:RER_49240 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Putative GntR family transcriptional regulator. | Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767: IPR000700; KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein. | 0.464 |
| Tlie_0182 | Tlie_0183 | PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: rer:RER_49240 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Putative GntR family transcriptional regulator. | CoA-binding domain protein; PFAM: CoA binding domain; Formyl transferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR002376: IPR003781; KEGG: mpd:MCP_2918 acetyl-CoA synthetase; PFAM: CoA-binding domain protein; formyl transferase domain protein; SPTR: Acetyl coenzyme A synthetase (ADP forming), alpha domain protein. | 0.773 |
| Tlie_0182 | Tlie_0184 | PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: rer:RER_49240 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Putative GntR family transcriptional regulator. | Pyruvate carboxyltransferase; PFAM: HMGL-like; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034: IPR000891; KEGG: aco:Amico_1308 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.698 |
| Tlie_0182 | Tlie_0185 | PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: rer:RER_49240 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Putative GntR family transcriptional regulator. | PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839; KEGG: cth:Cthe_0363 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate/tyrosine/aromatic aminotransferase. | 0.704 |
| Tlie_0182 | Tlie_0186 | PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: rer:RER_49240 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Putative GntR family transcriptional regulator. | PFAM: Sodium:neurotransmitter symporter family; COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: aoe:Clos_2599 sodium:neurotransmitter symporter; PFAM: sodium:neurotransmitter symporter; SPTR: Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. | 0.495 |
| Tlie_0183 | Tlie_0181 | CoA-binding domain protein; PFAM: CoA binding domain; Formyl transferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR002376: IPR003781; KEGG: mpd:MCP_2918 acetyl-CoA synthetase; PFAM: CoA-binding domain protein; formyl transferase domain protein; SPTR: Acetyl coenzyme A synthetase (ADP forming), alpha domain protein. | Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767: IPR000700; KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein. | 0.492 |
| Tlie_0183 | Tlie_0182 | CoA-binding domain protein; PFAM: CoA binding domain; Formyl transferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR002376: IPR003781; KEGG: mpd:MCP_2918 acetyl-CoA synthetase; PFAM: CoA-binding domain protein; formyl transferase domain protein; SPTR: Acetyl coenzyme A synthetase (ADP forming), alpha domain protein. | PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: rer:RER_49240 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Putative GntR family transcriptional regulator. | 0.773 |
| Tlie_0183 | Tlie_0184 | CoA-binding domain protein; PFAM: CoA binding domain; Formyl transferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR002376: IPR003781; KEGG: mpd:MCP_2918 acetyl-CoA synthetase; PFAM: CoA-binding domain protein; formyl transferase domain protein; SPTR: Acetyl coenzyme A synthetase (ADP forming), alpha domain protein. | Pyruvate carboxyltransferase; PFAM: HMGL-like; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034: IPR000891; KEGG: aco:Amico_1308 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.730 |
| Tlie_0183 | Tlie_0185 | CoA-binding domain protein; PFAM: CoA binding domain; Formyl transferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR002376: IPR003781; KEGG: mpd:MCP_2918 acetyl-CoA synthetase; PFAM: CoA-binding domain protein; formyl transferase domain protein; SPTR: Acetyl coenzyme A synthetase (ADP forming), alpha domain protein. | PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839; KEGG: cth:Cthe_0363 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate/tyrosine/aromatic aminotransferase. | 0.750 |
| Tlie_0183 | Tlie_0186 | CoA-binding domain protein; PFAM: CoA binding domain; Formyl transferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR002376: IPR003781; KEGG: mpd:MCP_2918 acetyl-CoA synthetase; PFAM: CoA-binding domain protein; formyl transferase domain protein; SPTR: Acetyl coenzyme A synthetase (ADP forming), alpha domain protein. | PFAM: Sodium:neurotransmitter symporter family; COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: aoe:Clos_2599 sodium:neurotransmitter symporter; PFAM: sodium:neurotransmitter symporter; SPTR: Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. | 0.514 |
| Tlie_0184 | Tlie_0181 | Pyruvate carboxyltransferase; PFAM: HMGL-like; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034: IPR000891; KEGG: aco:Amico_1308 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767: IPR000700; KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein. | 0.453 |
| Tlie_0184 | Tlie_0182 | Pyruvate carboxyltransferase; PFAM: HMGL-like; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034: IPR000891; KEGG: aco:Amico_1308 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524: IPR011711; KEGG: rer:RER_49240 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR domain protein; SMART: regulatory protein GntR HTH; SPTR: Putative GntR family transcriptional regulator. | 0.698 |
| Tlie_0184 | Tlie_0183 | Pyruvate carboxyltransferase; PFAM: HMGL-like; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034: IPR000891; KEGG: aco:Amico_1308 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | CoA-binding domain protein; PFAM: CoA binding domain; Formyl transferase; COGs: COG1042 Acyl-CoA synthetase (NDP forming); InterPro IPR002376: IPR003781; KEGG: mpd:MCP_2918 acetyl-CoA synthetase; PFAM: CoA-binding domain protein; formyl transferase domain protein; SPTR: Acetyl coenzyme A synthetase (ADP forming), alpha domain protein. | 0.730 |
| Tlie_0184 | Tlie_0185 | Pyruvate carboxyltransferase; PFAM: HMGL-like; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034: IPR000891; KEGG: aco:Amico_1308 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839; KEGG: cth:Cthe_0363 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate/tyrosine/aromatic aminotransferase. | 0.787 |
| Tlie_0184 | Tlie_0186 | Pyruvate carboxyltransferase; PFAM: HMGL-like; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR002034: IPR000891; KEGG: aco:Amico_1308 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; SPTR: Pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | PFAM: Sodium:neurotransmitter symporter family; COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: aoe:Clos_2599 sodium:neurotransmitter symporter; PFAM: sodium:neurotransmitter symporter; SPTR: Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. | 0.553 |
| Tlie_0185 | Tlie_0181 | PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839; KEGG: cth:Cthe_0363 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate/tyrosine/aromatic aminotransferase. | Diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014: IPR000160: IPR013767: IPR000700; KEGG: sat:SYN_02543 PAS sensory box/GGDEF family protein; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein. | 0.422 |