STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0190Signal transduction histidine kinase, LytS; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Predicted histidine kinase sensor domain; COGs: COG3275 Putative regulator of cell autolysis; InterPro IPR018771: IPR010559: IPR003594: IPR005467; KEGG: cpf:CPF_1171 sensor histidine kinase; PFAM: Transcription regulator,histidine kinase sensor-like; histidine kinase internal region; ATP-binding region ATPase domain protein; SPTR: Histidine kinase. (405 aa)    
Predicted Functional Partners:
Tlie_0191
Two component transcriptional regulator, AraC family; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789: IPR018060: IPR018062: IPR000005; KEGG: tjr:TherJR_0615 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Two component transcriptional regulator [...]
 
  
 0.968
Tlie_1798
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1840 ABC-type Fe3+ transport system periplasmic component; InterPro IPR006059; KEGG: cag:Cagg_2416 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1.
 
 
   0.895
Tlie_0195
Microcompartments protein; PFAM: BMC domain; COGs: COG4816 Ethanolamine utilization protein; InterPro IPR000249: IPR009193; KEGG: tex:Teth514_1954 microcompartments protein; PFAM: microcompartments protein; SPTR: Microcompartments protein.
 
  
 0.716
Tlie_0208
ATP/cobalamin adenosyltransferase; PFAM: Domain of unknown function (DUF336); Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase; COGs: COG2096 conserved hypothetical protein; InterPro IPR017858: IPR002779: IPR005624; KEGG: tjr:TherJR_0629 ATP/cobalamin adenosyltransferase; PFAM: protein of unknown function DUF336; cobalamin adenosyltransferase; SPTR: ATP/cobalamin adenosyltransferase; TIGRFAM: ATP/cobalamin adenosyltransferase.
  
  
 0.704
Tlie_0284
Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR003661: IPR003594: IPR003660: IPR 005467; KEGG: azl:AZL_a10370 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase [...]
 
  
 0.696
Tlie_0196
PFAM: Dehydratase large subunit; COGs: COG4909 Propanediol dehydratase large subunit; InterPro IPR003206; KEGG: tex:Teth514_1953 glycerol dehydratase; PFAM: dehydratase large subunit; PRIAM: Glycerol dehydratase; SPTR: Glycerol dehydratase.
 
   
 0.644
Tlie_0197
PFAM: Dehydratase medium subunit; InterPro IPR003208; KEGG: dal:Dalk_4998 dehydratase medium subunit; PFAM: dehydratase medium subunit; SPTR: Glycerol dehydratase, medium subunit.
 
   
 0.635
Tlie_0209
PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR012408; KEGG: tjr:TherJR_0630 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: CoA-dependent propionaldehyde dehydrogenase.
 
   
 0.623
panD
L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
       0.618
Tlie_0192
Microcompartments protein; PFAM: BMC domain; COGs: COG4810 Ethanolamine utilization protein; InterPro IPR000249: IPR009307; KEGG: tai:Taci_0087 microcompartments protein; PFAM: microcompartments protein; SPTR: Ethanolamine utilization protein EutS.
     
 0.587
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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