STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0225Flavodoxin/nitric oxide synthase; PFAM: Flavodoxin; Metallo-beta-lactamase superfamily; COGs: COG0426 flavoprotein; InterPro IPR001226: IPR008254: IPR016440; KEGG: dal:Dalk_2373 beta-lactamase domain protein; PFAM: flavodoxin/nitric oxide synthase; SPTR: Beta-lactamase domain protein. (401 aa)    
Predicted Functional Partners:
Tlie_1656
PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR001763: IPR013027: IPR004099: IPR000815; KEGG: tai:Taci_0103 pyridine nucleotide-disulphide oxidoreductase dimerization region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 0.932
Tlie_0791
PFAM: Flavin reductase like domain; COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: tai:Taci_1579 flavin reductase domain protein FMN-binding protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Flavin reductase domain protein FMN-binding protein.
   
 0.930
Tlie_0048
PFAM: Desulfoferrodoxin; Desulfoferrodoxin, N-terminal domain; TIGRFAM: desulfoferrodoxin FeS4 iron-binding domain; desulfoferrodoxin; desulfoferrodoxin ferrous iron-binding domain; COGs: COG2033 Desulfoferrodoxin; InterPro IPR004462: IPR004793: IPR002742; KEGG: tme:Tmel_1201 desulfoferrodoxin; PFAM: Desulfoferrodoxin ferrous iron-binding region; Desulfoferrodoxin Dfx domain protein; SPTR: Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin.
  
 0.844
Tlie_0224
PFAM: Rubrerythrin; COGs: COG1592 Rubrerythrin; InterPro IPR003251: IPR004039: IPR009040; KEGG: dol:Dole_2647 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin.
 
  
 0.787
Tlie_0049
Rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin; COGs: COG1773 Rubredoxin; InterPro IPR001052: IPR018527: IPR004039; KEGG: tme:Tmel_1197 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin.
 
  
 0.582
Tlie_1355
PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027; KEGG: aco:Amico_1237 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
   
 0.525
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
 
   
 0.525
Tlie_1142
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.471
Tlie_0331
PFAM: BFD-like [2Fe-2S] binding domain; InterPro IPR007419; KEGG: glo:Glov_2254 BFD domain protein (2Fe-2S)-binding domain protein; PFAM: BFD domain protein [2Fe-2S]-binding domain protein; SPTR: BFD domain protein (2Fe-2S)-binding domain protein.
  
  
 0.448
Tlie_0953
PFAM: BFD-like [2Fe-2S] binding domain; InterPro IPR007419; KEGG: tai:Taci_0969 BFD domain protein (2Fe-2S)-binding domain protein; PFAM: BFD domain protein [2Fe-2S]-binding domain protein; SPTR: BFD domain protein (2Fe-2S)-binding domain protein.
  
  
 0.448
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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