STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0237CRISPR-associated protein, Csm4 family; TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm4; COGs: COG1567 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005510: IPR005537; KEGG: tnp:Tnap_1018 CRISPR-associated RAMP protein, Csm4 family; PFAM: protein of unknown function DUF324; SPTR: CRISPR-associated RAMP protein, Csm4 family; TIGRFAM: CRISPR-associated RAMP protein, Csm4 family. (308 aa)    
Predicted Functional Partners:
Tlie_0236
CRISPR-associated protein, Csm3 family; PFAM: RAMP superfamily; TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm3; COGs: COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR013412: IPR005537; KEGG: tpt:Tpet_1095 CRISPR-associated RAMP Csm3 family protein; PFAM: protein of unknown function DUF324; SPTR: Putative uncharacterized protein; TIGRFAM: CRISPR-associated RAMP protein, Csm3 family.
 
 
 0.998
Tlie_0238
PFAM: RAMP superfamily; TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm5; COGs: COG1332 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR010173: IPR005537; KEGG: mvu:Metvu_1225 CRISPR-associated RAMP protein, Csm5 family; PFAM: protein of unknown function DUF324; SPTR: Putative uncharacterized protein; TIGRFAM: CRISPR-associated RAMP protein, Csm5 family.
 
 
 0.998
Tlie_0235
CRISPR-associated protein, Csm2 family; PFAM: Protein of unknown function (DUF310); TIGRFAM: CRISPR type III-A/MTUBE-associated protein Csm2; InterPro IPR010149; KEGG: tnp:Tnap_1016 CRISPR-associated protein, Csm2 family; PFAM: CRISPR-associated protein TM1810 domain protein; SPTR: Putative uncharacterized protein; TIGRFAM: CRISPR-associated protein, Csm2 family.
  
 
 0.986
Tlie_0240
CRISPR-associated protein, Cas6 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
 
     0.890
Tlie_0241
Protein of unknown function DUF48; PFAM: CRISPR associated protein Cas1; COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729; KEGG: bfr:BF2544 hypothetical protein; PFAM: protein of unknown function DUF48; SPTR: Putative uncharacterized protein; manually curated.
 
     0.801
Tlie_0239
Hypothetical protein; KEGG: ote:Oter_4003 glycosyl transferase group 1; SPTR: Putative uncharacterized protein.
       0.773
Tlie_0260
CRISPR-associated protein, Cas6 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
 
     0.440
cas2-2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.421
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.