STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0281Transmembrane transport protein; PFAM: Natural resistance-associated macrophage protein; COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; KEGG: tai:Taci_0711 transmembrane transport protein; SPTR: Transporter. (416 aa)    
Predicted Functional Partners:
Tlie_0277
PFAM: Protein of unknown function (DUF1445); COGs: COG4336 conserved hypothetical protein; InterPro IPR009906: IPR016938; KEGG: aco:Amico_0499 protein of unknown function DUF1445; PFAM: protein of unknown function DUF1445; SPTR: Putative uncharacterized protein; Belongs to the D-glutamate cyclase family.
    0.961
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
 0.838
Tlie_0280
PFAM: Allophanate hydrolase subunit 1; TIGRFAM: TIGR00370 family protein; COGs: COG2049 Allophanate hydrolase subunit 1; InterPro IPR003833: IPR010016; KEGG: aco:Amico_0496 allophanate hydrolase subunit 1; PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; SPTR: Allophanate hydrolase, subunit 1.
  
 0.816
Tlie_0279
Urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain; COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: aco:Amico_0497 UreA amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; PRIAM: Urea carboxylase; SMART: Allophanate hydrolase subunit 2; SPTR: Urea amidolyase related protein; TIGRFAM: urea amidolyase related protein.
  
 0.762
Tlie_0152
ABC-3 protein; PFAM: ABC 3 transport family; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: mar:MAE_52810 ABC-3 transport family protein; PFAM: ABC-3 protein; SPTR: Similar to A1IAV0_9DELT Putative Mn/Zn ABC transporter.
   
  
 0.759
Tlie_0285
PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: amt:Amet_2980 Na+/solute symporter; PFAM: Na+/solute symporter; SPTR: Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
   
 0.556
Tlie_0283
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR020441: IPR001789: IPR003593: IPR002078: IPR 002197; KEGG: ddf:DEFDS_1402 two-component system, NtrC family, response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase [...]
 
     0.506
Tlie_0282
PFAM: Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymerase sigma-54 factor; COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR001901: IPR007046: IPR007634; KEGG: ddf:DEFDS_1044 DNA-directed RNA polymerase sigma 54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; SPTR: RNA polymerase, sigma 54 subunit, RpoN.
     
 0.442
Tlie_0284
Integral membrane sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR003661: IPR003594: IPR003660: IPR 005467; KEGG: azl:AZL_a10370 two-component sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase [...]
       0.440
Tlie_0153
PFAM: ABC transporter; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593: IPR003439; KEGG: syp:SYNPCC7002_A2500 ABC transporter; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter.
  
  
 0.429
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.