STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0367Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926: IPR005856: IPR005859: IPR000634; KEGG: aco:Amico_0096 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase A; TIGRFAM: cysteine synthase; cysteine synthase A. (306 aa)    
Predicted Functional Partners:
Tlie_0368
TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451: IPR005881; KEGG: dtu:Dtur_1260 serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase.
 
 0.998
Tlie_1507
PFAM: Cys/Met metabolism PLP-dependent enzyme; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: gtn:GTNG_2270 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase.
 
 0.971
Tlie_1671
Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926: IPR005479; KEGG: cdl:CDR20291_1562 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase A.
  
  
 
0.919
Tlie_1732
Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: aco:Amico_0198 pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Pyridoxal-5'-phosphate-dependent protein beta subunit.
  
  
 
0.911
cysS
PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR001943: IPR015803: IPR015273: IPR002308; KEGG: aco:Amico_1002 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteine--tRNA ligase; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.909
Tlie_1179
PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR001176: IPR004839; KEGG: aco:Amico_1183 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II.
   
 0.906
Tlie_1476
PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dba:Dbac_2014 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II.
   
 0.906
Tlie_0291
PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR003726: IPR000489: IPR003759: IPR006158; KEGG: tai:Taci_0141 homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; SPTR: Vitamin B12-dependent methionine synthase family protein.
  
 
 0.886
Tlie_0870
Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR020082: IPR015878; KEGG: aco:Amico_1031 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase.
  
 0.842
Tlie_0167
O-acetylhomoserine sulfhydrolase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235: IPR000277; KEGG: tai:Taci_1506 O-acetylhomoserineaminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine aminocarboxypropyltransferase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase.
 
 
 0.838
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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