STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0396PFAM: Thiamine transporter protein (Thia_YuaJ); TIGRFAM: putative proton-coupled thiamine transporter YuaJ; COGs: COG3859 membrane protein; InterPro IPR012651; KEGG: aco:Amico_0262 proton-coupled thiamine transporter YuaJ; PFAM: thiamine transporter YuaJ; SPTR: Proton-coupled thiamine transporter YuaJ; TIGRFAM: proton-coupled thiamine transporter YuaJ. (166 aa)    
Predicted Functional Partners:
Tlie_0034
Membrane protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
  
   
 0.686
Tlie_0679
PFAM: Cobalt transport protein; COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: aco:Amico_0660 cobalt transport protein; PFAM: cobalt transport protein; SPTR: Cobalt transport protein.
  
  
 0.510
Tlie_1194
Transcriptional regulator, CdaR; PFAM: Putative sugar diacid recognition; COGs: COG3835 Sugar diacid utilization regulator; InterPro IPR008599; KEGG: aco:Amico_0355 transcriptional regulator, CdaR; PFAM: sugar diacid recognition domain protein; SPTR: Transcriptional regulator, CdaR.
  
     0.490
Tlie_1426
Helix-turn-helix protein YlxM/p13 family protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.421
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.