node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tlie_0429 | Tlie_0611 | Tlie_0429 | Tlie_0611 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | 0.932 |
Tlie_0429 | Tlie_0712 | Tlie_0429 | Tlie_0712 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: aco:Amico_0694 membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein; SPTR: Membrane protein insertase, YidC/Oxa1 family; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; manually curated. | 0.988 |
Tlie_0429 | ffh | Tlie_0429 | Tlie_1425 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.973 |
Tlie_0429 | ftsY | Tlie_0429 | Tlie_1080 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.975 |
Tlie_0429 | rplM | Tlie_0429 | Tlie_0431 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.966 |
Tlie_0429 | rplU | Tlie_0429 | Tlie_1005 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.930 |
Tlie_0429 | rpmF | Tlie_0429 | Tlie_1107 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; COGs: COG0333 Ribosomal protein L32; InterPro IPR002677; KEGG: tai:Taci_1103 ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: 50S ribosomal protein L32; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.926 |
Tlie_0429 | secA | Tlie_0429 | Tlie_1329 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.988 |
Tlie_0429 | secE | Tlie_0429 | Tlie_0444 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.996 |
Tlie_0429 | secY | Tlie_0429 | Tlie_0666 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.988 |
Tlie_0611 | Tlie_0429 | Tlie_0611 | Tlie_0429 | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.932 |
Tlie_0611 | Tlie_0712 | Tlie_0611 | Tlie_0712 | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: aco:Amico_0694 membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein; SPTR: Membrane protein insertase, YidC/Oxa1 family; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; manually curated. | 0.924 |
Tlie_0611 | ffh | Tlie_0611 | Tlie_1425 | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.925 |
Tlie_0611 | ftsY | Tlie_0611 | Tlie_1080 | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.926 |
Tlie_0611 | rplM | Tlie_0611 | Tlie_0431 | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.711 |
Tlie_0611 | rplU | Tlie_0611 | Tlie_1005 | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.592 |
Tlie_0611 | rpmF | Tlie_0611 | Tlie_1107 | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; COGs: COG0333 Ribosomal protein L32; InterPro IPR002677; KEGG: tai:Taci_1103 ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: 50S ribosomal protein L32; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.735 |
Tlie_0611 | secA | Tlie_0611 | Tlie_1329 | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.922 |
Tlie_0611 | secE | Tlie_0611 | Tlie_0444 | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.950 |
Tlie_0611 | secY | Tlie_0611 | Tlie_0666 | PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: aco:Amico_0591 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.942 |