STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0434PFAM: Bacterial regulatory proteins, tetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: aco:Amico_0301 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: Transcriptional regulator, TetR family. (203 aa)    
Predicted Functional Partners:
Tlie_0435
PFAM: Outer membrane efflux protein; COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: aco:Amico_0302 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein.
     
 0.841
Tlie_0436
PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: aco:Amico_0303 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 0.809
Tlie_0437
Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: aco:Amico_0304 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
     
 0.789
Tlie_0438
KEGG: aco:Amico_0305 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.784
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.717
Tlie_0505
Protein of unknown function DUF2229, CoA enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR011461: IPR002731: IPR018709; KEGG: pmo:Pmob_1610 CoA-substrate-specific enzyme activase; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; ATPase BadF/BadG/BcrA/BcrD type; protein of unknown function DUF1567; SPTR: Putative CoA-substrate-specific enzyme activase.
     
 0.619
Tlie_0433
Magnesium transporter; Acts as a magnesium transporter.
     
 0.548
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.547
Tlie_0440
PFAM: ABC transporter; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003439: IPR003593: IPR017871; KEGG: tte:TTE1863 ABC-type multidrug transport system, ATPase component; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Bacitracin transport ATP-binding protein BcrA.
  
  
 0.538
Tlie_0441
ABC-type transport, permease protein; COGs: COG1277 ABC-type transport system involved in multi-copper enzyme maturation permease component; InterPro IPR017871; KEGG: bth:BT_0926 ABC-type transport, permease protein; SPTR: ABC-type transport system.
 
   
 0.523
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.