STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0486PFAM: Iron-containing alcohol dehydrogenase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: cbh:CLC_1475 alcohol dehydrogenase, iron-containing; PFAM: iron-containing alcohol dehydrogenase; SPTR: Alcohol dehydrogenase, iron-containing. (399 aa)    
Predicted Functional Partners:
Tlie_0209
PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590: IPR012408; KEGG: tjr:TherJR_0630 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: CoA-dependent propionaldehyde dehydrogenase.
 
 0.941
Tlie_0488
PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR008250: IPR005834: IPR006404: IPR 006416: IPR001757: IPR018303: IPR001366; KEGG: dol:Dole_0421 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrola [...]
  
    0.512
Tlie_0487
PFAM: Bacterial regulatory protein, arsR family; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: fma:FMG_0053 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: ArsR family transcriptional regulator.
       0.507
Tlie_0484
PFAM: ABC transporter; CBS domain; COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterPro IPR003439: IPR000644: IPR003593: IPR017871; KEGG: tra:Trad_1572 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit.
     
 0.483
Tlie_0482
PFAM: Substrate binding domain of ABC-type glycine betaine transport system; COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: yen:YE2865 putative substrate-binding transport protein; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system.
     
 0.482
Tlie_0483
PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: yen:YE2864 putative ABC transport integral membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component.
     
 0.482
Tlie_0485
PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: bmj:BMULJ_05007 osmoprotectant transport system permease protein; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Putative ABC transporter system permease.
     
 0.482
Tlie_0481
Lysine exporter protein (LYSE/YGGA); PFAM: LysE type translocator; InterPro IPR001123; KEGG: cli:Clim_1754 lysine exporter protein (LysE/YggA); PFAM: Lysine exporter protein (LYSE/YGGA); SPTR: Lysine exporter protein (LYSE/YGGA).
  
    0.455
Tlie_0472
Zinc/iron permease; PFAM: ZIP Zinc transporter; COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: cbf:CLI_1259 ZIP family zinc transporter; PFAM: zinc/iron permease; SPTR: Zinc transporter, ZIP family.
  
    0.427
Tlie_0505
Protein of unknown function DUF2229, CoA enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); COGs: COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain); InterPro IPR011461: IPR002731: IPR018709; KEGG: pmo:Pmob_1610 CoA-substrate-specific enzyme activase; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; ATPase BadF/BadG/BcrA/BcrD type; protein of unknown function DUF1567; SPTR: Putative CoA-substrate-specific enzyme activase.
   
  
 0.426
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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