STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0488PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006121: IPR008250: IPR005834: IPR006404: IPR 006416: IPR001757: IPR018303: IPR001366; KEGG: dol:Dole_0421 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrola [...] (729 aa)    
Predicted Functional Partners:
Tlie_1359
PFAM: Heavy-metal-associated domain; InterPro IPR017969: IPR006121; KEGG: aco:Amico_1897 heavy metal transport/detoxification protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Heavy metal transport/detoxification protein.
  
 
 0.956
Tlie_0487
PFAM: Bacterial regulatory protein, arsR family; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: fma:FMG_0053 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: ArsR family transcriptional regulator.
 
  
 0.955
Tlie_0486
PFAM: Iron-containing alcohol dehydrogenase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: cbh:CLC_1475 alcohol dehydrogenase, iron-containing; PFAM: iron-containing alcohol dehydrogenase; SPTR: Alcohol dehydrogenase, iron-containing.
  
    0.512
Tlie_0899
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.453
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.