STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0545PFAM: Surface antigen variable number repeat; Surface antigen; COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827: IPR000184; KEGG: aco:Amico_1507 surface antigen (D15); PFAM: surface antigen (D15); surface antigen variable number repeat-containing protein; SPTR: Membrane protein, OMP85 family. (593 aa)    
Predicted Functional Partners:
Tlie_0550
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.962
Tlie_0547
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; COGs: COG1044 UDP-3-O-(3-hydroxymyristoyl); InterPro IPR001451: IPR007691: IPR018357; KEGG: aco:Amico_1505 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; SPTR: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase.
 
  
 0.960
Tlie_0690
Outer membrane chaperone Skp (OmpH); PFAM: Outer membrane protein (OmpH-like); InterPro IPR005632; KEGG: tai:Taci_0682 outer membrane chaperone Skp (OmpH); PFAM: outer membrane chaperone Skp (OmpH); SPTR: Outer membrane chaperone Skp (OmpH).
 
  
 0.957
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.934
Tlie_0552
PFAM: Predicted permease YjgP/YjgQ family; COGs: COG0795 permease; InterPro IPR005495; KEGG: aco:Amico_1500 permease YjgP/YjgQ family protein; PFAM: permease YjgP/YjgQ family protein; SPTR: Permease YjgP/YjgQ family protein.
 
   
 0.919
Tlie_0548
UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family.
 
   
 0.915
Tlie_0554
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.884
Tlie_0555
Hypothetical protein; PFAM: Lipid-A-disaccharide synthetase; COGs: COG0763 Lipid A disaccharide synthetase; KEGG: aco:Amico_1497 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.876
Tlie_0572
S-layer domain-containing protein; PFAM: S-layer homology domain; InterPro IPR001119; KEGG: aco:Amico_1484 S-layer domain protein; PFAM: S-layer domain-containing protein; SPTR: S-layer domain protein.
 
   
 0.838
Tlie_0573
S-layer domain-containing protein; PFAM: S-layer homology domain; InterPro IPR001119; KEGG: aco:Amico_1484 S-layer domain protein; PFAM: S-layer domain-containing protein; SPTR: S-layer protein.
 
   
 0.826
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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