node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tlie_0597 | Tlie_0598 | Tlie_0597 | Tlie_0598 | KEGG: aco:Amico_0579 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: cac:CA_C3548 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated. | 0.777 |
Tlie_0597 | murJ | Tlie_0597 | Tlie_0596 | KEGG: aco:Amico_0579 hypothetical protein; SPTR: Putative uncharacterized protein. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.737 |
Tlie_0597 | tsaD | Tlie_0597 | Tlie_0599 | KEGG: aco:Amico_0579 hypothetical protein; SPTR: Putative uncharacterized protein. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.822 |
Tlie_0598 | Tlie_0597 | Tlie_0598 | Tlie_0597 | KEGG: cac:CA_C3548 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated. | KEGG: aco:Amico_0579 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.777 |
Tlie_0598 | murJ | Tlie_0598 | Tlie_0596 | KEGG: cac:CA_C3548 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.693 |
Tlie_0598 | tsaD | Tlie_0598 | Tlie_0599 | KEGG: cac:CA_C3548 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.777 |
Tlie_0637 | Tlie_0948 | Tlie_0637 | Tlie_0948 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: aco:Amico_0792 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: Putative uncharacterized protein. | 0.655 |
Tlie_0637 | Tlie_0949 | Tlie_0637 | Tlie_0949 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Peptidase M22 glycoprotease; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: aco:Amico_0793 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease. | 0.659 |
Tlie_0637 | tsaD | Tlie_0637 | Tlie_0599 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.708 |
Tlie_0948 | Tlie_0637 | Tlie_0948 | Tlie_0637 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: aco:Amico_0792 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: Putative uncharacterized protein. | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.655 |
Tlie_0948 | Tlie_0949 | Tlie_0948 | Tlie_0949 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: aco:Amico_0792 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: Putative uncharacterized protein. | Peptidase M22 glycoprotease; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: aco:Amico_0793 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease. | 0.999 |
Tlie_0948 | tsaD | Tlie_0948 | Tlie_0599 | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: aco:Amico_0792 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: Putative uncharacterized protein. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.933 |
Tlie_0949 | Tlie_0637 | Tlie_0949 | Tlie_0637 | Peptidase M22 glycoprotease; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: aco:Amico_0793 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease. | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.659 |
Tlie_0949 | Tlie_0948 | Tlie_0949 | Tlie_0948 | Peptidase M22 glycoprotease; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: aco:Amico_0793 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease. | Uncharacterized protein family UPF0079, ATPase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: aco:Amico_0792 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase; SPTR: Putative uncharacterized protein. | 0.999 |
Tlie_0949 | guaA | Tlie_0949 | Tlie_0602 | Peptidase M22 glycoprotease; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: aco:Amico_0793 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.481 |
Tlie_0949 | tsaD | Tlie_0949 | Tlie_0599 | Peptidase M22 glycoprotease; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: aco:Amico_0793 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Peptidase M22 glycoprotease. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.965 |
dnaG | guaA | Tlie_0606 | Tlie_0602 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.402 |
dnaG | rsmA | Tlie_0606 | Tlie_1118 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.432 |
dnaG | tsaD | Tlie_0606 | Tlie_0599 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.658 |
gpsA | tsaD | Tlie_0361 | Tlie_0599 | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR011128: IPR006109: IPR006168; KEGG: aco:Amico_1622 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.639 |