STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0620PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753: IPR004000; KEGG: aco:Amico_0601 cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; SMART: actin/actin family protein; SPTR: Cell shape determining protein, MreB/Mrl family; TIGRFAM: cell shape determining protein, MreB/Mrl family. (347 aa)    
Predicted Functional Partners:
Tlie_0621
PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC; COGs: COG1792 Cell shape-determining protein; InterPro IPR007221; KEGG: aco:Amico_0602 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC.
 
 
 0.982
Tlie_0623
Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460: IPR017790; KEGG: tai:Taci_1207 penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: penicillin-binding protein 2.
 
 0.964
Tlie_0848
COGs: COG1426 conserved hypothetical protein; KEGG: tai:Taci_1663 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 0.902
Tlie_0627
PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182: IPR011923; KEGG: aco:Amico_0608 rod shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Rod shape-determining protein RodA; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family.
 
 
 0.892
Tlie_0622
PFAM: rod shape-determining protein MreD; KEGG: aco:Amico_0603 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.735
minC
Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
  
  
 0.732
Tlie_0617
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
  
 0.725
Tlie_0625
PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD; COGs: COG2894 Septum formation inhibitor-activating ATPase; InterPro IPR010223; KEGG: aco:Amico_0606 septum site-determining protein MinD; SPTR: Septum site-determining protein MinD; TIGRFAM: septum site-determining protein MinD.
  
 
 0.725
Tlie_0619
Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: tai:Taci_1211 beta-lactamase domain protein; SPTR: Beta-lactamase domain protein.
       0.700
dtd
D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
       0.699
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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