STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0623Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460: IPR017790; KEGG: tai:Taci_1207 penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: penicillin-binding protein 2. (576 aa)    
Predicted Functional Partners:
Tlie_0977
PFAM: Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: aco:Amico_0818 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; Belongs to the SEDS family.
 0.995
Tlie_0627
PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182: IPR011923; KEGG: aco:Amico_0608 rod shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Rod shape-determining protein RodA; TIGRFAM: rod shape-determining protein RodA; Belongs to the SEDS family.
 
 0.992
Tlie_0621
PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC; COGs: COG1792 Cell shape-determining protein; InterPro IPR007221; KEGG: aco:Amico_0602 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC.
 
 
 0.970
Tlie_0620
PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753: IPR004000; KEGG: aco:Amico_0601 cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; SMART: actin/actin family protein; SPTR: Cell shape determining protein, MreB/Mrl family; TIGRFAM: cell shape determining protein, MreB/Mrl family.
 
 0.964
Tlie_0972
Peptidoglycan glycosyltransferase; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460; KEGG: tai:Taci_0866 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase.
  
  
 
0.921
Tlie_0681
PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: tai:Taci_1149 cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; SPTR: Cell shape determining protein, MreB/Mrl family; TIGRFAM: cell shape determining protein, MreB/Mrl family.
 
 0.885
Tlie_0622
PFAM: rod shape-determining protein MreD; KEGG: aco:Amico_0603 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.823
minC
Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
  
  
 0.701
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
 0.701
Tlie_0617
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
  
 0.674
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.