STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0700Protein of unknown function DUF107; PFAM: Clp protease; NfeD-like; COGs: COG1030 Membrane-bound serine protease (ClpP class); InterPro IPR002810; KEGG: aco:Amico_0686 protein of unknown function DUF107; PFAM: protein of unknown function DUF107; SPTR: Putative uncharacterized protein. (449 aa)    
Predicted Functional Partners:
Tlie_0701
PFAM: SPFH domain / Band 7 family; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR018080: IPR001107: IPR001972; KEGG: tai:Taci_0697 band 7 protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: Band 7 protein.
 
  
 0.969
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
       0.807
leuS
PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR001412: IPR002300: IPR013155: IPR002302; KEGG: tai:Taci_0698 leucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase.
       0.568
Tlie_0703
TIGRFAM: DNA polymerase III, delta subunit; COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372; KEGG: aco:Amico_0689 DNA polymerase III delta; PFAM: DNA polymerase III delta; SPTR: Putative uncharacterized protein.
       0.568
Tlie_0698
PFAM: Sodium:solute symporter family; COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: aco:Amico_0718 Na+/solute symporter; PFAM: Na+/solute symporter; SPTR: Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
       0.501
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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