STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0713PFAM: R3H domain; COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: aco:Amico_0695 single-stranded nucleic acid binding R3H domain protein; PFAM: single-stranded nucleic acid binding R3H domain-containing protein; SMART: single-stranded nucleic acid binding R3H domain-containing protein; SPTR: Single-stranded nucleic acid binding R3H domain protein. (220 aa)    
Predicted Functional Partners:
Tlie_0712
PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708: IPR020001; KEGG: aco:Amico_0694 membrane protein insertase, YidC/Oxa1 family; PFAM: 60 kDa inner membrane insertion protein; SPTR: Membrane protein insertase, YidC/Oxa1 family; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; manually curated.
 
  
 0.953
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
  
  
 0.921
Tlie_0711
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.914
Tlie_1423
Hypothetical protein; PFAM: KH domain; COGs: COG1837 RNA-binding protein (contains KH domain); KEGG: aco:Amico_0553 hypothetical protein; SPTR: Putative uncharacterized protein; Belongs to the UPF0109 family.
   
 
 0.880
Tlie_0630
Ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family; COGs: COG1530 Ribonuclease G and E; InterPro IPR018247: IPR003029: IPR019307: IPR004659; KEGG: aco:Amico_0611 ribonuclease, Rne/Rng family; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein; SPTR: Ribonuclease, Rne/Rng family; TIGRFAM: ribonuclease, Rne/Rng family.
   
   0.832
rsmG
16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.757
rpmH
PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; InterPro IPR000271: IPR020939; KEGG: csc:Csac_2776 50S ribosomal protein L34; PFAM: ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: ribosomal protein L34; manually curated; Belongs to the bacterial ribosomal protein bL34 family.
     
 0.752
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
   
  
 0.729
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
    0.704
rplV
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
   
    0.697
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.