STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mutS2MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (782 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
 
0.941
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.849
rpsD
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
    
   0.848
Tlie_0353
PFAM: PHP domain; COGs: COG1796 DNA polymerase IV (family X); InterProIPR004013: IPR002054: IPR003583: IPR003141: IPR 002008; KEGG: ttr:Tter_1075 PHP domain protein; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein; SPTR: Cell division topological specificity factor MinE.
  
  
 0.823
Tlie_0737
PFAM: Colicin V production protein; COGs: COG1286 membrane protein required for colicin V production; InterPro IPR003825; KEGG: aco:Amico_0713 colicin V production protein; PFAM: Colicin V production protein; SPTR: Colicin V production protein.
       0.823
rpmI
PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35; InterPro IPR001706: IPR018265: IPR021137; KEGG: tai:Taci_0725 ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
   
   0.820
Tlie_0736
KEGG: aco:Amico_0712 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
Tlie_0936
PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA); COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616: IPR008532; KEGG: aco:Amico_0959 fibronectin-binding A domain protein; PFAM: protein of unknown function DUF814; Fibronectin-binding A domain protein; SPTR: Fibronectin-binding A domain protein.
 
     0.768
rpsU
PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; InterPro IPR001911: IPR018278; KEGG: aco:Amico_1436 ribosomal protein S21; PFAM: ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
 
 
   0.747
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.729
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.