STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (457 aa)    
Predicted Functional Partners:
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
 0.993
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 0.971
dacA
Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
   
 
 0.915
Tlie_0762
UDP-glucose pyrophosphorylase; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835: IPR005771; KEGG: tai:Taci_0840 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; SPTR: UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase.
    
 0.823
Tlie_1237
PFAM: Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: aco:Amico_1360 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase family protein.
 
  
 0.807
Tlie_0760
PFAM: YbbR-like protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: aco:Amico_0738 YbbR family protein; PFAM: YbbR family protein; SPTR: YbbR family protein.
  
  
 0.785
Tlie_0755
PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterProIPR018209: IPR015793: IPR015794: IPR008279: IPR 001697; KEGG: tai:Taci_0833 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.784
Tlie_0358
Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; PFAM: HD domain; Poly A polymerase head domain; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646: IPR006674: IPR006675; KEGG: dae:Dtox_0608 polynucleotide adenylyltransferase/metal dependent phosphohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: Poly A polymerase; TIGRFAM: metal dependent phophohydrolase.
    
 0.683
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
  
 0.665
Tlie_0991
Hypothetical protein; Displays ATPase and GTPase activities.
 
   
 0.660
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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