STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0779Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (142 aa)    
Predicted Functional Partners:
Tlie_0889
Thymidine phosphorylase; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase; COGs: COG0213 Thymidine phosphorylase; InterProIPR000053: IPR017872: IPR017459: IPR000312: IPR 013102: IPR018090; KEGG: aco:Amico_1012 pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase domain; glycosyl transferase family 3; Glycosyl transferase, family 3-like; PRIAM: Thymidine phosphorylase; SPTR: Pyrimidine-nucleoside phosphorylase; TI [...]
 
 0.994
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
  
 0.955
Tlie_0888
Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
 
 0.935
Tlie_1554
AAA ATPase; PFAM: Phosphoribulokinase / Uridine kinase family; COGs: COG0572 Uridine kinase; InterPro IPR000764: IPR003593; KEGG: tai:Taci_1361 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase.
 
  
 0.930
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.911
Tlie_0775
PFAM: PhoH-like protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: aco:Amico_0752 PhoH family protein; PFAM: PhoH family protein; SPTR: PhoH family protein; manually curated.
  
    0.875
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.857
Tlie_0781
DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
  
 0.845
Tlie_0778
PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644: IPR002550: IPR005170; KEGG: aco:Amico_0755 protein of unknown function DUF21; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; SPTR: Putative uncharacterized protein.
  
    0.820
Tlie_0776
7TM receptor with intracellular metal dependent phosphohydrolase; PFAM: 7TM-HD extracellular; HD domain; TIGRFAM: uncharacterized domain HDIG; COGs: COG1480 membrane-associated HD superfamily hydrolase; InterPro IPR011621: IPR006674: IPR006675: IPR003607; KEGG: aco:Amico_0753 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; metal-dependent phosphohydrolase 7TM intracellular region; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase.
       0.769
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.