STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0792Conserved hypothetical protein CHP02757; PFAM: Protein of unknown function (DUF2400); TIGRFAM: TIGR02757 family protein; InterPro IPR014127; KEGG: aco:Amico_0403 hypothetical protein; PFAM: Conserved hypothetical protein CHP02757; SPTR: Putative uncharacterized protein. (277 aa)    
Predicted Functional Partners:
Tlie_0016
Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth); COGs: COG0708 Exonuclease III; InterPro IPR000097: IPR004808: IPR005135; KEGG: aco:Amico_1607 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth.
  
 0.925
Tlie_0791
PFAM: Flavin reductase like domain; COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; InterPro IPR002563; KEGG: tai:Taci_1579 flavin reductase domain protein FMN-binding protein; PFAM: flavin reductase domain protein FMN-binding; SPTR: Flavin reductase domain protein FMN-binding protein.
       0.787
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
  
 
 0.657
Tlie_1197
DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; DNA polymerase family A; 5'-3' exonuclease, N-terminal resolvase-like domain; TIGRFAM: DNA polymerase I; COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR019760: IPR002421: IPR008918: IPR001098: IPR 002298: IPR018320: IPR020046: IPR020047; KEGG: aco:Amico_1259 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain [...]
  
 
 0.609
mntP
Protein of unknown function DUF204; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.
       0.572
Tlie_0793
KEGG: tai:Taci_1571 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.566
Tlie_0795
PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR016473: IPR016192: IPR002125; KEGG: aco:Amico_0406 CMP/dCMP deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: ComE operon protein 2.
  
    0.559
Tlie_0796
AAA ATPase central domain protein; PFAM: ATPase family associated with various cellular activities (AAA); InterProIPR019734: IPR013026: IPR003959: IPR001440: IPR 000641: IPR003593; KEGG: nth:Nther_1502 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; Tetratricopeptide TPR_1 repeat-containing protein; SMART: AAA ATPase; Tetratricopeptide repeat; SPTR: AAA ATPase central domain protein.
     
 0.528
Tlie_1199
PFAM: 4Fe-4S binding domain; TIGRFAM: electron transport complex, RnfABCDGE type, B subunit; COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR017900: IPR017896; KEGG: aco:Amico_1262 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
  
 0.518
Tlie_0790
PFAM: Permease family; TIGRFAM: uracil-xanthine permease; COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042: IPR006043; KEGG: aco:Amico_0396 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil/vitamin C permease.
     
 0.515
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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