Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Tlie_0804PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain; COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR011108; KEGG: aco:Amico_0410 beta-lactamase domain protein; PFAM: RNA-metabolising metallo-beta-lactamase; SPTR: Beta-lactamase domain protein; manually curated. (537 aa)    
Predicted Functional Partners:
Tlie_0083
KEGG: tai:Taci_0287 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.951
Tlie_0365
PFAM: Tetratricopeptide repeat; COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR001440: IPR019734: IPR013026; KEGG: cyh:Cyan8802_1328 peptidase S1 and S6 chymotrypsin/Hap; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: Peptidase S1 and S6 chymotrypsin/Hap.
  
 0.884
Tlie_1197
DNA polymerase I; PFAM: 5'-3' exonuclease, C-terminal SAM fold; DNA polymerase family A; 5'-3' exonuclease, N-terminal resolvase-like domain; TIGRFAM: DNA polymerase I; COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR019760: IPR002421: IPR008918: IPR001098: IPR 002298: IPR018320: IPR020046: IPR020047; KEGG: aco:Amico_1259 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain [...]
  
 0.848
Tlie_0353
PFAM: PHP domain; COGs: COG1796 DNA polymerase IV (family X); InterProIPR004013: IPR002054: IPR003583: IPR003141: IPR 002008; KEGG: ttr:Tter_1075 PHP domain protein; PFAM: PHP domain protein; SMART: DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; phosphoesterase PHP domain protein; SPTR: Cell division topological specificity factor MinE.
 
 
 0.800
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.797
Tlie_0805
PFAM: Outer membrane efflux protein; COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: aco:Amico_0486 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein.
       0.773
Tlie_0808
KEGG: aco:Amico_0411 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.758
sbcD
Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
 0.757
Tlie_0807
Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: aco:Amico_0352 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
    0.751
Tlie_1123
RNA polymerase Rpb6; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  0.751
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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