node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tlie_0866 | Tlie_0870 | Tlie_0866 | Tlie_0870 | KEGG: aco:Amico_1035 hypothetical protein; SPTR: Putative uncharacterized protein. | Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR020082: IPR015878; KEGG: aco:Amico_1031 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase. | 0.679 |
Tlie_0866 | mtaD | Tlie_0866 | Tlie_0871 | KEGG: aco:Amico_1035 hypothetical protein; SPTR: Putative uncharacterized protein. | Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.642 |
Tlie_0866 | mtnA | Tlie_0866 | Tlie_0869 | KEGG: aco:Amico_1035 hypothetical protein; SPTR: Putative uncharacterized protein. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.739 |
Tlie_0866 | mutL | Tlie_0866 | Tlie_0875 | KEGG: aco:Amico_1035 hypothetical protein; SPTR: Putative uncharacterized protein. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.494 |
Tlie_0866 | mutS | Tlie_0866 | Tlie_0874 | KEGG: aco:Amico_1035 hypothetical protein; SPTR: Putative uncharacterized protein. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.494 |
Tlie_0866 | nusB | Tlie_0866 | Tlie_0867 | KEGG: aco:Amico_1035 hypothetical protein; SPTR: Putative uncharacterized protein. | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.794 |
Tlie_0866 | xseA | Tlie_0866 | Tlie_0868 | KEGG: aco:Amico_1035 hypothetical protein; SPTR: Putative uncharacterized protein. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.767 |
Tlie_0870 | Tlie_0866 | Tlie_0870 | Tlie_0866 | Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR020082: IPR015878; KEGG: aco:Amico_1031 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase. | KEGG: aco:Amico_1035 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.679 |
Tlie_0870 | mtaD | Tlie_0870 | Tlie_0871 | Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR020082: IPR015878; KEGG: aco:Amico_1031 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase. | Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | 0.860 |
Tlie_0870 | mtnA | Tlie_0870 | Tlie_0869 | Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR020082: IPR015878; KEGG: aco:Amico_1031 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.774 |
Tlie_0870 | mutL | Tlie_0870 | Tlie_0875 | Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR020082: IPR015878; KEGG: aco:Amico_1031 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.666 |
Tlie_0870 | mutS | Tlie_0870 | Tlie_0874 | Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR020082: IPR015878; KEGG: aco:Amico_1031 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.622 |
Tlie_0870 | nusB | Tlie_0870 | Tlie_0867 | Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR020082: IPR015878; KEGG: aco:Amico_1031 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase. | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.703 |
Tlie_0870 | xseA | Tlie_0870 | Tlie_0868 | Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR020082: IPR015878; KEGG: aco:Amico_1031 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.725 |
folD | nusB | Tlie_1721 | Tlie_0867 | 5, 10-methylenetetrahydrofolate dehydrogenase (NADP+), methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.775 |
folD | xseA | Tlie_1721 | Tlie_0868 | 5, 10-methylenetetrahydrofolate dehydrogenase (NADP+), methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.954 |
mtaD | Tlie_0866 | Tlie_0871 | Tlie_0866 | Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | KEGG: aco:Amico_1035 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.642 |
mtaD | Tlie_0870 | Tlie_0871 | Tlie_0870 | Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase; COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043: IPR020082: IPR015878; KEGG: aco:Amico_1031 adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding; S-adenosyl-L-homocysteine hydrolase; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase. | 0.860 |
mtaD | mtnA | Tlie_0871 | Tlie_0869 | Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.793 |
mtaD | mutL | Tlie_0871 | Tlie_0875 | Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.656 |