STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_0923PFAM: Protein of unknown function (DUF448); COGs: COG2740 nucleic-acid-binding protein implicated in transcription termination; InterPro IPR007393; KEGG: aco:Amico_0974 protein of unknown function DUF448; PFAM: protein of unknown function DUF448; SPTR: Ribosomal protein L7Ae family protein. (220 aa)    
Predicted Functional Partners:
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
  
    0.976
rimP
Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
  
 0.968
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
  
 0.961
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
  
    0.886
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
    0.867
Tlie_0929
Riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; COGs: COG0196 FAD synthase; InterPro IPR002606: IPR015864: IPR015865; KEGG: tai:Taci_0988 riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; Belongs to the ribF family.
 
    0.863
Tlie_0640
PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; KEGG: tai:Taci_1190 ribosomal protein L7AE family protein; SPTR: Ribosomal protein L7AE family protein.
  
  
 0.841
Tlie_0927
Phosphoesterase RecJ domain protein; PFAM: DHHA1 domain; DHH family; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667: IPR003156; KEGG: aco:Amico_0969 phosphoesterase DHHA1; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein.
  
    0.829
Tlie_0925
PFAM: Protein of unknown function (DUF503); InterPro IPR007546; KEGG: aco:Amico_0971 protein of unknown function DUF503; PFAM: protein of unknown function DUF503; SPTR: Putative uncharacterized protein.
  
    0.817
Tlie_0464
KEGG: aco:Amico_0931 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.800
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.