STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tlie_1044Agmatinase; PFAM: Arginase family; TIGRFAM: agmatinase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR020855: IPR005925: IPR006035; KEGG: pth:PTH_0946 arginase/agmatinase/formimionoglutamate hydrolase; PFAM: Arginase/agmatinase/formiminoglutamase; SPTR: Agmatinase; TIGRFAM: agmatinase; Belongs to the arginase family. (288 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
 
 0.989
Tlie_1046
PFAM: Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; COGs: COG1945 conserved hypothetical protein; InterPro IPR000209: IPR002724; KEGG: hmo:HM1_1757 pyruvoyl-dependent arginine decarboxylase; PFAM: Pyruvoyl-dependent arginine decarboxylase; PRIAM: Arginine decarboxylase; SPTR: Arginine decarboxylase, pyruvoyl-dependent; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent.
 
  
 0.981
speH
S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
     
 0.808
Tlie_0373
PFAM: Formiminotransferase domain, N-terminal subdomain; Formiminotransferase domain; TIGRFAM: glutamate formiminotransferase; COGs: COG3643 Glutamate formiminotransferase; InterPro IPR012886: IPR013802: IPR004227; KEGG: tai:Taci_0915 glutamate formiminotransferase; PFAM: Formiminotransferase domain protein; Formiminotransferase domain protein; PRIAM: Glutamate formimidoyltransferase; SPTR: Glutamate formiminotransferase; TIGRFAM: glutamate formiminotransferase.
  
    0.778
hutH
PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: phenylalanine ammonia-lyase; histidine ammonia-lyase; COGs: COG2986 Histidine ammonia-lyase; InterPro IPR001106: IPR005921; KEGG: tai:Taci_0916 histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase.
  
  
 0.729
Tlie_0745
PFAM: Protein of unknown function (DUF1385); COGs: COG3872 metal-dependent protein; InterPro IPR010787; KEGG: aco:Amico_0724 protein of unknown function DUF1385; PFAM: protein of unknown function DUF1385; SPTR: Putative uncharacterized protein.
   
    0.703
Tlie_1041
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
 
   
 0.584
Tlie_1472
PFAM: Aminotransferase class-III; COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: tai:Taci_0450 aminotransferase class-III; PFAM: aminotransferase class-III; SPTR: Acetylornithine transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.580
arcA
Arginine deiminase; PFAM: Amidinotransferase; TIGRFAM: arginine deiminase; COGs: COG2235 Arginine deiminase; InterPro IPR003876: IPR003198; KEGG: tte:TTE0103 arginine deiminase; PFAM: amidinotransferase; PRIAM: Arginine deiminase; SPTR: Arginine deiminase.
     
 0.564
hutI
Imidazolonepropionase; PFAM: Amidohydrolase family; TIGRFAM: imidazolonepropionase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680: IPR005920; KEGG: aco:Amico_1885 imidazolonepropionase; PFAM: amidohydrolase; SPTR: Imidazolonepropionase; TIGRFAM: imidazolonepropionase.
  
  
 0.485
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.